Author: Sarah DeVido, MSc, FNTP,
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Abstract: Abnormal proteins have been linked to not only neurodegenerative diseases such as Parkinson’s and Alzheimer’s but also diseases such as several types of cancer and type 2 diabetes. These truncated or misfolded proteins can form extracellular deposits or intracellular inclusions associated with disease. Researchers are unsure of the exact mechanism but theorize it is most likely the disruption of protein homeostasis. As cells get overwhelmed by abnormal proteins, the mechanisms to package or break down these proteins become overwhelmed, and abnormal proteins start circulating through the body. In research studies, the disruption of protein homeostasis occurs quicker when there is a “seeding” mechanism- e.g., amyloids or amyloid fragments (abnormal proteins). Several animal studies report that when given an amyloid stimulus, inflamed animals develop amyloidosis, a disease of abnormal proteins in the blood. Commercial animals found to have amyloids include beef, chicken, and foie gras. Amyloid fibrils were found in various organs, glands, skeletal muscle, and cartilage, depending on disease severity. Researchers from the University of Tennessee stated, “Given our experimental findings, it would seem prudent for children and adults with Rheumatoid Arthritis or other diseases who are at risk for this disorder (amyloidosis) to avoid foods that may be contaminated with amyloid fibrils.”